A SYSTEMATIC REVIEW TO ALIGNING RESEARCH PATHS: ENERGY CYBER-PHYSICAL SYSTEMS



3-oxoacyl-ACP reductase from Schistosoma japonicum: integrated in silico-in vitro strategy for discovering antischistosomal lead compounds.

BACKGROUND: Schistosomiasis is a disease caused by parasitic worms and more than 200 million people are infected worldwide.The emergence of resistance to the most commonly used drug, praziquantel (PZQ), makes the development of novel drugs an urgent task.3-oxoacyl-ACP reductase (OAR), a key enzyme involved in the fatty acid synthesis pathway, has b

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